45 Of the 20,800 breast cancer research grants totaling $15 billion US that were extracted from the ICRP and HRA databases, 2281, or 11%, were identified as being relevant to MBC research. Those 2281 grants totaled $1.1 billion US, or 7.1% of the total investment. Funding for MBC research grew gradually over time, from 2% of the breast cancer research funding in 2000 to a peak of 9% in 2010 (Figure 5). In addition, the numbers of active MBC projects in a given year grew from 6% of the total number of breast cancer projects in 2000 to 15% in 2012. Note that the data for 2012 and 2013 are incomplete, as data from all ICRP and all HRA members have not been finalized for those years. The largest sources of MBC research funding identified from the MBC Grant Dataset were (from greatest to least dollar value of funding over time) as follows: the Department of Defense Congressionally Directed Medical Research Programs, NCI/National Institutes of Health, Canadian Cancer Research Alliance, Susan G. Komen, United Kingdom’s National Cancer Research Institute, National Breast Cancer Foundation (Australia), California Breast Cancer Research Program, American Cancer Society, Breast Cancer Research Foundation, Dutch Cancer Society (KWF), Avon Foundation, French National Cancer Institute, and the American Institute for Cancer Research. Note the Canadian Cancer Research Alliance and the United Kingdom’s National Cancer Research Institute are not direct funders of research; rather they are umbrella organizations that aggregate and collate national data from many individual funding organizations. Figure 5: Number and Amount of MBC Awards as a Function of Overall 
Breast Cancer Funding Black: funding for MBC research (% of total). Orange: active MBC projects (%). Note that the data for 2012 and 2013 are incomplete, as data from all ICRP and all HRA members have not been finalized for those years. 10% 20% 2000 2005 2010 FUNDING % AWARDS %