35 Table 1. Classification Schemes Used for Research Grants Abbreviations: CDK6 = cyclin-dependent kinase 6, CSO = Common Scientific Outline, MAPK = mitogen-activated protein kinases. Main Category Subcategory Metastatic stage (from Steps in Metastasis framework) • Invasion [5, 6] • Intravasation & circulation [6] • Arrest & extravasation[6] • Immune surveillance/escape[5, 6] • Metastatic colonization [6] • Metabolic deregulation [5] • Other • Not specified/not relevant Research stage (from CSO codes) 1. Basic 2. Translational 3. Clinical 4. Cancer control 5. Other Model System or Study Type • Preclinical research (model system/cell line/gene hunt) • Technologic developments (diagnostic/ prognostic/imaging) • Therapy/intervention Molecular Target • Free text (e.g., MAPK, CDK6) Pathway Free text (e.g., name of signalling pathway) Therapy/Intervention Free text (e.g., name of drug, therapy,or diagnostic tool)