This paper – from the same authors as the peer-reviewed opinion piece which appeared in the journal npj Breast Cancer on March 16, 2017 – summarizes published studies examining the reasons for an atypical response, new research initiatives that are exploring this topic, the strengths and limitations of these endeavors, and a call-to-action for strategic direction.
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Dr. Ruth Etzioni, a biostatistician in Fred Hutchinson Cancer Research Center’s Public Health Sciences Division, has received a five-year National Institutes of Health grant to advance the science of cancer surveillance by developing, validating and deploying a scalable, automated approach for identifying cancer recurrence.
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A retrospective analysis, reported in the journal Breast Cancer Research and Treatment, of more than 8,189 women with invasive breast cancer and 1,158 women diagnosed with metastatic breast cancer (MBC) between 1990 and 2010 identified differences in tumor characteristics and survival due to breast cancer in women diagnosed with de novo stage IV breast cancer (dnMBC) compared to those whose metastasis was the result of recurrent stage I-III disease (rMBC).
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Key Findings from MBC Alliance Key Opinion Leaders Think Tank Published in AACR Cancer Research
“Obstacles, Opportunities and Priorities for Advancing Metastatic Breast Cancer Research”
“Estimation of the Number of Women Living with Metastatic Breast Cancer in the United States”
The article is available to read or download here – Cancer Epidemiology, Biomarkers & Prevention